Therapy resistance and clinical trials in neuro-oncology

Research focus

The group is investigating mechanisms of resistance to chemo- and immunotherapeutic agents in brain tumors. Furthermore, novel treatment strategies are assessed in patients with newly diagnosed and recurrent glioblastoma.

• Overcoming resistance of gliomas to immunotherapeutic strategies
• Development of novel drugs in early clinical trials
• Design and conductance of late-stage clinical trials in neuro-oncology, including immunotherapeutic strategies such as immune checkpoint inhibition

Members:

• Michael Weller
• Yasmin Abdel Moneim
• Evelina Blomberg
• Clara Quijano Rubio
• Dorothee Gramatzki
• Katharina Seystahl
• Manuela Silginer
• Hans-Georg Wirsching
• Fabian Wolpert