Immunology in the CNS

Research focus

Our research aims to understand the development of tissue-specific inflammation in particular in the context of interactions of the nervous system with the immune system.

A part of our studies of autoimmunity (an undesired process) we we apply our tool-set and expertise to study the impact of immunity to combat cancer (a desired process).

Our main research interests can be categorized as such:

• Cytokine networks in chronic inflammatory disease with a focus on in vivo modeling of multiple sclerosis, psoriasis, graft-versus host disease
• Cancer-immunotherapy: specifically the interaction of immune cells with cancer cells and therapeutic interventions to mount immune responses against tumors
• High dimensional single cell mapping of immune responses, both in preclinical models of cancer and human patient biopsie material

Member:

• Burkhard Becher
• Ekatarina Friebel